Liver cancer is the third largest tumor in China and has a high mortality rate, which seriously threatens the health and quality of life of patients. As there are no obvious symptoms in the early stage of liver cancer, most patients are already in the middle and late stage when they are detected, which increases the difficulty of treatment. During the Cancer Awareness Week, early detection of liver cancer is not difficult, just an ultrasound and blood test (serum alpha-fetoprotein (AFP)) can “reveal” the liver cancer hidden in the body, and both tests have been included in medical insurance. 85% of liver cancer is caused by hepatitis and cirrhosis “85% of liver cancer patients are transformed from chronic hepatitis and cirrhosis.” “China is a large country with liver disease, and on average, 1 in 10 people is a hepatitis B carrier. And Guangdong has a large mobile population and many hepatitis patients, so the incidence of liver cancer is also high.” The development of liver cancer generally goes through the “trilogy” of hepatitis – cirrhosis – liver cancer. Research data shows that 15-20 percent of hepatitis patients will develop cirrhosis within five years, and 10-15 percent of cirrhosis patients will develop liver cancer. After the development of liver cancer, patients often have underlying liver diseases such as hepatitis and cirrhosis, which greatly increases the difficulty of treatment. To stop the occurrence of liver cancer, the first hurdle is not to have hepatitis, and the best way to prevent hepatitis is to receive various hepatitis vaccinations from infants. Without hepatitis B, the chances of cirrhosis are naturally reduced, and then the possibility of liver cancer is likewise reduced. In addition to liver cancer caused by cirrhosis due to hepatitis B, about 15% of liver cancer patients are not caused by hepatitis, but by other causes, such as alcohol, hepatitis C virus, parasites, aflatoxin, contaminated drinking water, certain micronutrient deficiencies, genetic factors, toxic chemicals containing benzene, certain drugs and other factors. Especially in spoiled rice, soybeans, peanut rice, melon seeds and other foods contain a large number of aflatoxin, which is the main factor that induces cancer. In addition, in the drugs for weight loss and diuretic, if it contains ingredients such as morpholinoic acid and ephedra, long-term consumption is also very damaging to the liver. Therefore, the prevention of liver cancer should be gated from two aspects: one is not to have hepatitis, and the other is not to add carcinogenic substances to oneself, so as to block the occurrence of liver cancer in the etiology. Checking methemoglobin every six months for people with high risk of liver cancer Most patients are already in the middle and late stages when liver cancer is detected, and the treatment effect of the disease is poor. Therefore, early diagnosis of the disease is crucial for liver cancer patients. Early detection of liver cancer is not difficult, just an ultrasound and a blood test (serum alpha-fetoprotein (AFP)) is all that is needed. For those with family history of liver cancer, those with more than 5 years of hepatitis or positive hepatitis B surface antigen, those with more than 5-8 years of alcoholism and those with confirmed cirrhosis, it is better to have blood test for AFP every 3-6 months and ultrasound examination every 6 months, and CT or MRI examination when there is suspicion, which can help detect liver cancer at an early stage. “Otherwise, by the time symptoms such as abdominal pain, wasting, jaundice and ascites appear and then come to see, it is already in the middle and late stage.” With the development of medical imaging, liver cancer lesions that can be detected are getting smaller and smaller, and the latest type of hepatocyte-specific contrast agent can detect tiny lesions below 1 cm. If you are not a high-risk group, it is also recommended to check AFP annually, “AFP detection of liver cancer should be quantitative, and checking qualitative sometimes misses the time for early diagnosis. When AFP is significantly elevated it often indicates liver malignancy, which has high specificity.” Besides early detection and treatment, what other methods can prevent liver cancer? 1.Wide vaccination against hepatitis B can effectively control the spread of hepatitis B. 2.Patients with hepatitis B undergo active antiviral treatment, which can reduce the damage of virus to liver, protect liver cells and inhibit the progress of liver disease. 3, can not ignore the destruction of the liver by alcohol, quit smoking and drinking habits can avoid the stimulation of the liver. 4. In terms of diet, patients with liver disease should avoid smoking, alcohol and spicy food, eat more fresh vegetables and fruits, increase protein intake in appropriate amount, and reduce animal protein intake and avoid greasy food for patients with severely impaired liver function. Treatment of liver cancer emphasizes individualized treatment plan “For the treatment of liver cancer, it is no longer the era of various lords showing their skills, but emphasizes individualized treatment plan with multidisciplinary collaboration.” “Individualized treatment for liver cancer should not only incorporate the tumor itself, but also be based on the patient’s systemic condition and the degree of liver damage.” Commonly used treatment methods in the field of liver cancer treatment include surgery, liver transplantation, local ablation interventional therapy, targeted therapy, biological therapy, etc. However, fewer patients with liver cancer are able to be detected early, and correspondingly, not many patients can be given the opportunity to be surgically removed. However, patients with liver cancer are often over-treated. Some patients, once detected as liver cancer, tend to be removed by surgery; some patients, who obviously have the chance of radical surgery, choose conservative treatment, and some even go to whichever specialty to be treated first. Multidisciplinary and comprehensive treatment is the current consensus in liver cancer treatment. In principle, surgical resection is the main treatment for early-stage hepatocellular carcinoma, local ablation can be considered for tumors below 3 cm in diameter, and liver transplantation is also an option. For most patients with intermediate and advanced hepatocellular carcinoma, a multidisciplinary integrated treatment approach including intervention, ablation, local radiotherapy and targeted drugs must be emphasized. Liver cancer is not so much a local cancer as a systemic disease in a sense, especially in the middle and late stages, some patients believe too much in certain new treatment methods and continue to carry out various local treatments for local liver masses even though their whole body has metastasized extensively, resulting in serious destruction of liver function, and some patients finally die not from tumor consumption and destruction, but from treatment-induced Liver failure. Therefore, no matter what kind of treatment is given, the damage to non-tumor tissues and cells should be avoided to the maximum extent possible. Targeted therapy brings the light and the hope of overcoming cancer in the future, but it should also be applied properly under the guidance of experts. According to him, the World Health Organization (WHO) has characterized malignant tumors as chronic diseases and classified them as controlled treatments like hypertension, diabetes, chronic bronchitis, etc. Under the influence of certain drugs, the life state can be adjusted so that patients can “live with tumors” with quality of life. For patients with mid- to late-stage hepatocellular carcinoma, they should look at the disease with a positive attitude and cooperate with the treatment while undergoing conventional treatment, so that they can “survive with tumor” to “survive well with tumor”, that is, to improve their quality of life and prolong their survival.