Positive herpes simplex virus (HSV) IgG suggests a possible herpes simplex virus infection. Herpes simplex virus IgG titers ≥1:16 are positive, suggesting secondary infection. A double serum IgG antibody titer of 4-fold and above is indicative of recent herpes simplex virus infection. Herpes simplex viruses are divided into type I and type II viruses. Type I viruses not only cause herpetic keratoconjunctivitis, oropharyngeal herpes, cutaneous herpetic eczema and encephalitis, but may also cause latent infection and re-emergence with latent sites in the superior cervical ganglion and trigeminal ganglion. Type II virus is mainly transmitted through close contact and sexual contact, and the latent site of the virus is the sacral ganglion, and the latent virus can be activated after stimulation, causing recurrent infection, so patients with herpes simplex virus IgG positive should be tested and treated promptly. Daily exercise should be done to improve the body immunity. Pay attention to rest on time, avoid staying up late and overworking, and try to eat lightly and ensure regular rest and rest to prevent herpes recurrence. You should also be careful not to use other people’s towels, washbasins, dishes, etc., not to wear other people’s clothes, and not to take showers in public bathrooms to prevent virus transmission. In case of severe symptoms, anti-infection treatment with drugs such as acyclovir and famciclovir can be applied under the guidance of a doctor.