Herpes simplex viruses have many opportunities for transmission in the human population. These viruses are widely parasitic in the human body, with microscopic injuries to the body and close contact being the main means of transmission. There are two types of herpes simplex viruses: type I, which causes skin herpes above the waist, oral herpes and keratoconjunctivitis; and type II, which causes skin herpes below the waist and external genital herpes. When a pregnant woman is infected with herpes simplex virus, it can be transmitted to the fetus through the placenta and, if the birth canal is infected, to the newborn during delivery. The prognosis for these newborns is poor, with a high mortality rate, high neurological sequelae in survivors, and blindness in untreated corneal lesions. Herpes simplex virus infection is not 100% certain to be transmitted to the fetus, but amniotic fluid examination should be done promptly and pregnancy should be terminated if the amniotic fluid is positive. For mothers with obstetric tract infection, a cesarean section should be performed before or 3 hours after the water breaks to protect the newborn from infection. It should also be noted that to protect the newborn from infection, all children and adults with herpes stomatitis should not be exposed to the newborn, including doctors, nursing staff and midwives. Herpes simplex virus infection during pregnancy can be localized or systemic. The former is milder, with localized infections occurring on the face, hands and feet, corners of the lips, genitals, eyes, etc. The infected areas are visible as rice-sized blisters, several or a dozen in a row, accompanied by fever or swollen local lymph nodes. Most of the systemic infections are critical and may result in anemia and serious lesions of the nervous, respiratory and circulatory systems. The effects on the fetus include: 1. Pregnancy combined with herpes simplex virus infection can cause intrauterine infection in the fetus, increasing the rate of stillbirth and miscarriage. 2, early pregnancy combined with herpes simplex virus infection, can be transmitted through the placenta and reproductive system, causing intrauterine infection of the fetus and malformations, such as microcephaly, small eyes, retinal hypoplasia and brain calcification. 3, primary herpes simplex virus infection in pregnant women, the preterm birth rate increased, preterm infants also significantly higher rate of detection of herpes simplex virus than full-term children, which is related to the virus caused by the decline in pregnancy immunity. 4, the fetal central nervous system infection herpes simplex virus, can cause fetal death and malformation. 5. Herpes simplex virus infection in pregnant women can cause scarring conjunctivitis and keratitis in newborns when delivered vaginally; gangrene, cyanosis, inhalation difficulties, shock, drowsiness, dementia and coma in systemic infections. The mother who has been infected with herpes simplex virus should pay attention during delivery: 1. To prevent the fetus and newborn from being infected with herpes simplex virus during vaginal delivery, the fetus should be removed by cesarean section, regardless of whether the mother has primary or recurrent genital infection with herpes simplex virus. 2. Those infected with herpes simplex virus in late pregnancy are highly susceptible to early rupture of membranes and preterm delivery. If you have any suspicion of herpes simplex virus infection, you should take cervical mucus for virus culture and serological examination before delivery. If the fetus is already deformed, it can be delivered naturally. For patients with occult herpes simplex virus infection, amniotic fluid examination can be performed before delivery to determine whether there is intrauterine infection of herpes simplex virus and to choose the mode of delivery. The treatment and prevention of herpes simplex in pregnancy: generally mild herpes simplex is a self-limiting disease and does not require extraordinary treatment. 1, local treatment: herpes simplex keratitis and conjunctivitis, available 0.1% herpes net eye drops, once every hour during the day, once every 2 hours at night, for 3 days can control the development. Genital herpes simplex can also be applied with 40 % herpes net. 2. Systemic treatment: Herpes simplex vaccine and cytarabine can be used for treatment. 3, prevention: pregnant women pay attention to the hygiene of sexual life, strengthen exercise, improve health. When the mother is infected with herpes simplex virus, she should actively prevent fetal and neonatal infections. Focus on prevention and control of reproductive system infection in late pregnancy and appropriate choice of delivery method is crucial.