(Disclaimer: This article is for scientific purposes only, and the information in the following content has been processed to protect patient privacy)
Abstract: A 23-year-old female presented with recurrent small blisters of a painful nature on the perioral and genital surfaces, with occasional rupture of the blisters resulting in significant vesiculation and exudative changes, recurring several times a year. The actual fact is that you can find a lot of people who are not able to get a lot of money for the actual money.
Basic Information】Female, 23 years old
Disease Type】Perioral herpes simplex, genital herpes
Hospital】Harbin Hospital of Traditional Chinese Medicine
Time】April 2022
Treatment Plan】Medication (Valacyclovir Hydrochloride Tablets + Penciclovir Cream + Thymidine Enteric Solution Tablets)
Treatment period】7 days of home treatment, 1 month of telephone follow-up
Effectiveness】Blisters gradually dried up and disappeared, pain disappeared, recurrence rate decreased
I. First interview
The patient described that she had painful blisters around the corners of her mouth, not for the first time, but for many years, and that the blisters recurred several times a year. On examination, we found a large blister at the junction of the skin and mucous membrane at the corner of the patient’s mouth and a similar small blister on the labia of the external genitalia, which was accompanied by significant pain when not touched, according to the patient’s overall description, consistent with a disease caused by herpes simplex virus infection. According to the specifics of the disease, a herpes simplex virus antibody test was done, and the test results showed positive herpes simplex 1 virus IgG and positive herpes simplex 2 virus IgM. Based on the laboratory test results, combined with clinical manifestations to support the diagnosis of herpes simplex virus infection as perioral herpes simplex and genital herpes, respectively.
II. Treatment history
The patient had been suffering from this disease for many years, and recently the skin damage in the perioral and genital areas had recurred at the same time, thus seriously affecting the patient’s quality of life. The patient was then given a treatment plan based on his status, with oral medication such as valacyclovir hydrochloride tablets and topical medication such as topical penciclovir cream, which was applied continuously until the symptoms on the skin surface had completely disappeared and then discontinued. After the symptoms completely disappeared, the patient was instructed to buy thymidine enteric soluble tablets and take them for a full course of treatment in order to improve the immunity of the body and reduce the probability of recurrence of the disease.
Third, the effect of treatment
Perioral herpes simplex and genital herpes caused by herpes simplex virus infection are very easy to recur, the virus will be latent in the body, but when the symptoms appear, it will affect the quality of life of patients, so active treatment can improve the quality of life, respectively, after 7 days and 1 month of the patient’s medication to call back. According to the patients’ feedback, the pain of lips and vulva was obviously reduced after 2 days of medication, and the small blisters on the surface of lips and genitals gradually dried up and subsided in about 5 days, and completely returned to the normal state in 7 days. And after 1 month of using thymidine enteric dissolve tablet, the patient feels that the physical condition is obviously improved and no recurrence of disease is seen at present.
IV. Precautions
The patient felt very relieved to recover from the discomfort symptoms through medication. It should be noted that perioral herpes simplex and genital herpes are both caused by herpes simplex virus infection and are contagious, so try not to have direct contact with others to avoid infecting healthy people through contact. In addition, it is recommended to avoid alcohol and spicy food to avoid the effect of the medication. The medication should be used in accordance with the doctor’s instructions, so that the symptoms on the surface of the skin can subside as soon as possible.
V. Personal insights
1, after the herpes simplex virus infection is caused, respectively, may be different due to the type of virus infection, perioral herpes simplex and genital herpes, need to be based on laboratory tests for a clear diagnosis, do not judge based on clinical manifestations alone, to avoid misdiagnosis, to prevent confusion with diseases such as leukodystrophy.
2, the probability of recurrence of this disease is relatively high, may be based on the strength of the patient’s own immunity to recurrence, so in addition to regular antiviral drug treatment, but also need to improve the immunity of the patient’s body, which can reduce the probability of recurrence;.
3, because the disease itself can lead to sexual transmission, so after the appearance of symptoms, avoid sexual relations with others, and recommended to actively go to the relevant hospital for formal consultation and treatment, as the patient, after treatment can achieve good results;.
4, after taking the drug if nausea, vomiting, regurgitation and other uncomfortable symptoms, it is recommended to consult a doctor at the hospital in a timely manner and replace other drugs for alternative treatment to avoid affecting the therapeutic effect and adversely affecting the health.