How effective is radiation therapy in the local treatment of liver cancer?

  There are more patients with liver cancer in China, and surgery is the best treatment modality that can remove liver cancer, but most patients have no chance of surgery when they are found. With the development of radiotherapy technology, precise radiotherapy can protect as much normal liver tissue and surrounding vital organs as possible, making it possible to increase the dose of radiotherapy. Radiotherapy is playing an increasing role in the treatment of liver cancer, either alone or in combination with TACE in a complementary manner. Several international clinical studies have shown promising results, both in terms of local control rates and overall survival.  Since 2013, the US NCCN guidelines have recommended radiation therapy as an important tool for local treatment of liver cancer.  Specific recommendations are as follows: 1. External radiation (stereotactic radiation therapy or 3D conformal radiation therapy) can be considered for all tumors.  2. Stereotactic radiation therapy is an advanced technique for external radiation as it can be given at a large dose.  SBRT can be used as an alternative treatment to radiofrequency ablation and arterial embolization.  4. Patients for whom stereotactic radiation therapy is indicated usually have no more than three lesions. If enough normal liver is preserved, large lesions or progressive hepatocellular carcinoma can also be treated with radiotherapy.  5.For hepatocellular carcinoma that has metastasized, radiation therapy for liver lesions can reduce symptoms and control tumor development.