Acne vulgaris is also commonly referred to as “acne”. It is a chronic inflammatory disease of the sebaceous glands of the hair follicles. The pathogenesis of acne vulgaris is the formation of abnormal pimples, caused by the blockage of keratin plugs in the lower part of the follicle and the expansion of the follicle. Acne vulgaris mainly affects the face, neck and chest and back. It is clinically characterized by acne, papules, pustular nodules, and often scarring. Patients usually present with different lesions at different stages of disease progression and remission. In dark-colored individuals, hyperpigmentation is often seen and can persist for several months. Acne scarring is most commonly seen as broken ice pick-like scarring on the temporal and cheek areas, as well as canyon shaped atrophic scarring on the face, which not only causes cosmetic problems for the patient, but also creates psychological shadows. Acne often begins in adolescence, and may also begin in women between the ages of 20 and 35 in late adolescence. Some women may experience an increase in papulopustular lesions about a week before menstruation. Treatment of acne vulgaris includes oral and topical medications. The main topical medications are retinoids, such as adapalene gel and isotretinoin gel. Benzoyl peroxide gel and antibiotics can also be used topically. It usually takes 6 to 8 weeks of medication to judge the efficacy. It is required that the entire area affected by acne should be treated, not just limited to the lesions. For patients with moderate to severe acne, a combination of oral antibiotics and topical adapalene gel may be used. 6 to 8 weeks of medication is required to evaluate the efficacy, and some oral medications require a course of 3 to 6 months. Therefore, it needs to be emphasized that long-term medication should become routine. Daily oral and topical medications are also emphasized, as the essence of treatment is prevention. Topical treatment can also serve as an effective maintenance therapy after the condition has been brought under control by a combination of oral and topical therapy. The most common and important reason for treatment failure is lack of compliance, i.e., the patient does not follow the physician’s instructions. In order to achieve optimal compliance, it is crucial that the patient understands how the lesions are portrayed, the expected effects of treatment, the course of treatment and possible adverse effects, and receives clear instructions from the physician. Patients also need to understand the difference between an inflammatory lesion and a stable purplish red spot or hyperpigmented spot that has resolved. Patients should also correct some missteps. Vigorous scrubbing of the face not only causes greater irritation, but may also cause acne to worsen due to friction. A common problem is excessive washing, which some patients feel helps them get rid of blackheads and greasiness, but factors such as mechanical frictional irritation may irritate the follicle epithelium and cause acne and follicle rupture. Patients are also advised to use medically prescribed medications and avoid using over-the-counter medications that cause dry skin on their own, such as astringents, strong cleansers or antibiotic cleansing soaps. The use of non-comedogenic cosmetics is recommended, avoiding powders and products with an oily base.