How to achieve early detection and diagnosis of liver cancer People who do not have hepatitis B should be vaccinated; if they have hepatitis B, they should be treated early. People who have a history of hepatitis B or a family history of cancer, those who have a history of alcohol abuse for more than 5-8 years and suffer from clinical manifestations of chronic liver disease, and those who have been diagnosed with liver cirrhosis are all high-risk groups. These people need regular follow-up, and it is recommended to have a comprehensive examination of biochemical and imaging indicators of liver disease, including ultrasound and AFP, at least every six months. Once suspicious lesions are detected, further examinations such as CT should be done for clear diagnosis. CT has now become a routine item for liver cancer localization diagnosis, which can clarify the location, number, size and relationship with important blood vessels. It can indicate the nature of lesions, especially the enhanced scan, which can help to identify hemangioma. Our 64-row spiral enhanced CT can detect small hepatocellular carcinoma at an early stage. How to treat liver cancer In the 100 years since the first case of liver cancer was successfully removed in 1891, liver cancer has changed from an “incurable disease” to a curable disease. Until today, the worldwide consensus is that surgical treatment is still the most effective and clinically preferred method for primary liver cancer, and its role and status are still on the rise. Regular resection of hepatocellular carcinoma has indeed restored the hope of life for some patients with hepatocellular carcinoma, and the rapid development of AFP for screening and imaging technology in the 70s and 80s has opened up a new era of research on small hepatocellular carcinoma. These treatments have made it possible to achieve “surgical resection after shrinking unresectable liver cancer”. The goals of hepatocellular carcinoma treatment are firstly, surgical cure, secondly, prolonging the survival period, and thirdly, reducing the pain. Therefore, we advocate the principles of “early”, “comprehensive” and “aggressive” treatment. Early and effective treatment is the most important way to achieve radical cure and prolong survival, i.e. the smaller the tumor, the higher the 5-year survival rate after resection. By “aggressive” treatment, we mean that some patients with postoperative recurrence can be treated by surgery again. For those who are found to be unresectable at late stage, it has become a reality to apply infusion chemotherapy and radiation therapy to shrink the tumor before surgical resection. In conclusion, over the past 100 years, human beings have accumulated rich experience in fighting with the evil of liver cancer and have achieved a series of achievements.