It takes about 15-20 years for nephritis to develop into uremia. Chronic glomerulonephritis cannot be cured, and it usually takes 10-15 years from the onset of the disease to the appearance of abnormal kidney function; it takes 5-10 years from the appearance of mild abnormalities in kidney function to the development of uremia, but of course, this is only for patients with irregular treatment of nephritis. If regular treatment, effective control of blood pressure and urine protein, avoid infection and nephrotoxic drugs, it is possible to postpone the development of nephritis into uremia for more than 5 years, so that the quality of survival of patients will be greatly improved. Therefore, patients with nephritis must pay attention to regular and active treatment to delay the appearance of kidney failure as far back as possible.