Cancer patients with mild depression may manifest as quietness, inhibition, discouragement, lack of interest in various things, some loss of concentration and memory, as well as nervousness and insomnia. In case of severe depression, in addition to the above-mentioned manifestations, it may also manifest as mania and difficulty in controlling mood. If the above symptoms occur, the first step is to diagnose whether it is depression and how depressed it is through assessment. For most depressed patients, psychological, emotional and social support, as well as verbal communication, can improve depressive symptoms in most cases. In the case of major depression, medication is needed to maximize the relief of symptoms.