Soot poisoning is usually treated with early first aid, physical therapy, and medication. The toxic component of soot mainly comes from carbon monoxide produced by insufficient combustion, so the treatment of soot poisoning needs to be directed at carbon monoxide poisoning. Clinical treatment is divided into early first aid, physical therapy, drug therapy and so on. 1. Early first aid: first of all, evacuate the scene of poisoning, transfer to the environment of air circulation, unclothes, to ensure that the respiratory tract is unobstructed, give oxygen, and at the same time, immediately send to the doctor. 2. Physical therapy: including hyperbaric oxygen therapy, mechanical ventilation, etc. 3. Pharmacological treatment: combined with the patient’s condition, give dehydration, diuretic drugs such as mannitol, furosemide, etc., give hormonal drugs such as glucocorticoids, etc., give drugs to promote the recovery of brain cells, such as adenosine triphosphate, coenzyme A, cytochrome C, etc., and give drugs for the treatment of convulsions such as phenytoin sodium. Therefore, for soot poisoning, emergency self-help should be taken, and standardized medication should be given as prescribed by the doctor after sending to the doctor.