Gout is a joint-damaging disease caused by the disorder of purine metabolism in the body. Colchicine is a traditional drug for the treatment of acute attacks of gout, especially for patients with early attacks of gout, and has good clinical efficacy. However, colchicine has a large toxic effect on the human body, and inappropriate doses can easily affect the normal functions of the liver and kidneys, so it should be used under the guidance of a doctor. One of the symptoms of gout is recurrent gouty arthritis, which is a form of inflammation. Colchicine can reduce the activity of cell membranes such as neutrophils in the affected area and inhibit the adhesion, chemotaxis and phagocytosis of neutrophils, thereby relieving inflammatory reactions such as pain, redness and swelling in the affected joints. Colchicine can also reduce joint pain in gout patients by inhibiting the release of leukotrienes and prostaglandins. However, due to the obvious side effects, patients should choose the exact dose of the drug according to their condition and illness under the guidance of a professional doctor to avoid adverse consequences. In addition to colchicine, for patients whose acute gout symptoms have not been relieved for a long time, or for patients with chronic gout, uric acid-lowering treatment should also be the main focus. Commonly used drugs include allopurinol, febuxostat and other drugs that inhibit uric acid production, as well as benzbromarone, propoxur and other drugs that promote uric acid excretion, and at the same time can be combined with indomethacin, etoricoxib and other non-steroidal anti-inflammatory drugs, which can achieve the purpose of relieving joint swelling and joint pain, so as to effectively control the continued development of gout.