Osteoporosis is a systemic metabolic disease of the skeleton characterized by a decrease in bone mass, degeneration of the fine structure of bone tissue, thinning, fracture and reduction in the number of cancellous bone trabeculae; thinning of cortical bone, resulting in increased brittleness of bone and increased risk of fragility fracture. The main clinical manifestations of osteoporosis are pain, shortening of height, hunchback, fragility fracture, and respiratory disorders. Among them, osteoporotic pain is its most common and dominant clinical symptom. The most prominent features of osteoporotic pain are: generalized pain, no fixed pressure points, and the manifestation is mostly dull pain. The most common sites of bone pain are low back, hip and extremities, with low back pain being more common and spreading to both sides along the spine; the pain is aggravated by prolonged sitting and standing. Osteoporotic pain is light during the day and heavy at night. Because during the day, sitting, standing, walking slowly, often after changing position, will relieve the pain symptoms. At night, the pain increases when resting and turning over. The pain is most severe when waking up in the early morning because, when waking up in the early morning, the muscles of the body are stiff and the pain in the bones is increased, while the pain will be relieved after a slow activity to increase blood circulation. The pain will be aggravated if you cough hard and bend hard after exercise; the pain will also be aggravated when constipation is exerted and when you sit for a long time to defecate. The older the age, the higher the incidence, women’s symptoms are heavier than men’s, and women are heavier after menopause than before menopause. According to statistics, most patients with osteoporosis have limited low back pain; some patients have low back pain with radiating pain in the limbs; very few patients have not only low back pain, but also numbness in the limbs and intercostal neuralgia and weakness when flexing and extending the back. In patients with severe osteoporosis, there is more bone loss in the vertebral body, which can cause vertebral fracture, compression and deformation of the vertebral body, narrowing of the intervertebral foramen and compression of the nerve roots, and the patient shows numbness and weakness of the lower limbs and motor dysfunction. Studies have shown that up to 75% of patients with postmenopausal osteoporosis have low back pain. And 42.7% of patients who visited the hospital with bone pain had lower than normal bone mass. Bone pain is the most common symptom of osteoporosis, which actually occurs in a high percentage. If timely diagnosis and treatment are carried out in a regular hospital and reasonable medication is used under the guidance of a doctor, the pain can be effectively relieved.