Left spermatic varicocele causes infertility in men? A lot of clinical data shows that many young men suffer from left spermatic varicose vein. The rate of combined infertility among men with left spermatic varicose vein is also very high, and left spermatic varicose vein is one of the causes of infertility in male friends. So, what are the causes of infertility caused by left spermatic varicose vein? 1, varicocele damages the interstitial cells of the testis, reducing testosterone secretion, peripheral blood testosterone content is also reduced, while the blood oogenic hormone (FSH) and interstitial cell stimulating hormone (ICSH) increase, endocrine disruption, so as to interfere with the occurrence and maturation of sperm; 2, varicocele due to blood stagnation in the spermatic vein, will lead to increased temperature in the scrotum, testicular temperature can rise 1℃-2℃, the temperature continues to increase for a long time, which will affect the testes to produce sperm, thus causing azoospermia and oligospermia; the epididymis is also not conducive to the maturation of sperm. However, spermatogenesis disorders mainly occur in the primary spermatocyte and spermatocyte stages; 3. Semen stagnation, increased pressure in the spermatic vein, lack of oxygen and nutrients, affects the removal of metabolites, and therefore affects spermatogenesis and maturation; 4. Blood reflux when one side of the spermatic varicose vein brings substances produced by the adrenal glands and kidneys such as: steroids, 5-hydroxytryptamine, prostaglandins, etc. to the testes. 5- 5-Hydroxytryptamine is one of the toxins, which has a toxic effect on the testes, and prostaglandins reduce blood circulation to the testes, increase epididymal contraction, which is detrimental to sperm maturation and also affects sperm motility. These are the causes of infertility caused by left spermatic varicose vein. Once you suffer from varicocele, you must go to a regular hospital to receive treatment in time to avoid delaying the condition and increasing the difficulty of healing.