Bipolar has some similarities to depression. For example, they are both episodic illnesses, or what we call intermittent episodes. According to the previous view, the onset of the disease is a state of illness, abnormal state, and the intermittent period is completely normal after the attack is controlled. But now we can’t say that the intermittent period is completely normal, there are completely normal, some patients have residual symptoms during the intermittent period, but even if there are residual symptoms, to a large extent, still recovered. So bipolar disorder is characterized by intermittent episodes, which is similar to depression. One of the similarities between bipolar disorder and depression in terms of treatment is that they are both treatable. Many people can still adapt well to society through treatment, and their ability to work, live, interact and communicate can be mostly or completely maintained. However, in terms of treatment difficulty, bipolar is more difficult than depression. In particular, many patients with bipolar disorder start at a young age, and it is critical and difficult to stabilize their mood and keep them in a stable state during the initial years. The genetic background of bipolar disorder may be a bit greater. Bipolar disorder may have episodes that may be a little more frequent than depression. Without systematic treatment, the average number of episodes in the lifetime of a person with bipolar disorder may reach 14 or 15. The rate, the risk of suicide may be higher because of bipolar. And bipolar is not just a psychiatric disorder, it is also a systemic disorder. Therefore, the co-morbidity of bipolar patients is very high, and the co-morbidity of other diseases is very high. They are more likely to have co-morbidities with substance abuse, alcohol and drug abuse, personality disorders, cardiovascular diseases, metabolic diseases, hyperglycemia, hyperlipidemia, etc. than the general population. Patients diagnosed as bipolar are more likely to use oral hypoglycemic drugs and insulin injections than the general population, as well as patients with other mental disorders. In fact, if bipolar patients do not receive systematic treatment and do not control it as soon as possible, their working time will be shortened by 15 years and their life expectancy will be reduced by 5 years during their lifetime, which is the figure of international research.