It’s fall and winter again, and many of my friends often ask a question during their clinic visits: are the seasons related to the onset of psychiatric and psychological disorders? Do we need to increase the dose of medication? Scientifically, there is no correlation between the two, nor is there a causal relationship between the two. However, it is interesting to note that the occurrence of some diseases does have certain seasonal characteristics, which can easily cause misunderstanding to the public that seasonal changes will lead to the onset or recurrence of psychiatric disorders. Therefore, some patients or their families increase the dosage of medication as soon as the seasons change to prevent fluctuations in their conditions. In some cases, the medication is blindly reduced at the height of summer, leading to the occurrence of side effects of treatment or relapse of the disease. Although there is no necessary correlation between the two, some diseases do have some seasonal characteristics, the author introduces to the readers. Schizophrenia occurs in the alternating seasons of winter and spring, folk saying: cauliflower yellow, crazy crazy. Although the words are not elegant, but there is a certain truth, the author’s clinical findings over the years, a considerable portion of the patients in the winter and spring alternating seasons seizures or hospitalization, this time is also the busiest time of the hospital, therefore, at this time, generally do not advocate their own too quickly reduce the drug, even if the condition is more stable, but also not careless. Manic or bipolar disorder patients are more frequent in the alternating seasons of spring and summer, that is, early May and June, when some manic patients have more significant episodes, showing symptoms such as excitement, talking too much, self-aggrandizement, behavioral disorders, temper tantrums and insomnia. Whenever this season, the families of some old patients are also very vigilant for fear of relapse and fluctuation. For depression and anxiety disorders, obsessive-compulsive disorder and other diseases have not found obvious seasonal characteristics, any time may have an attack. In addition, female patients at different ages, the onset of the disease is also characterized, such as in adolescence prone to anxiety and depression and obsessive-compulsive symptoms, pregnancy or perinatal period prone to prenatal or postpartum anxiety and depression, in the menopause prone to mania, depression and somatization of symptoms. Therefore, for women, in the above age groups, they should pay attention to their emotional state and should not easily ignore it. In fact, regardless of the season, or different age groups, as long as the mind adjusts the law and rules, in and out of the degree, the balance of gains and losses, in order to truly do not be surprised by the spoils and insults, idle, smiling mouth always open ah!