What abnormalities may occur in the urine in renal tubular acidosis

After renal tubular acidosis, urine may show abnormal manifestations such as decreased specific gravity, increased urine volume, paradoxical alkalinity, and increased levels of potassium, calcium and phosphorus in the urine.
1. Decrease in specific gravity of urine: The ion reabsorption in distal renal tubules decreases, the ion exudation from distal renal tubules also decreases, the ion content in urine will be relatively less, so the specific gravity of urine will decrease.
2. Increased urine volume: patients with renal tubular acidosis often have different degrees of renal tubular function impairment, causing patients to increase urine volume.
3. Paradoxical alkaline urine: renal tubular damage, unable to carry out adequate acidification of urine, renal tubules are not able to secrete acidic substances and hydrogen ions, which may increase the pH value of urine, forming paradoxical alkaline urine.
4. Elevated levels of potassium, calcium and phosphorus in urine: potassium ions replace hydrogen ions to exchange with sodium ions, so that potassium ions are excreted from urine in large quantities. At the same time, acidosis can inhibit the reabsorption of calcium in renal tubules, so that patients present high urinary calcium and low blood calcium, and then secondary hyperparathyroidism, resulting in high urinary phosphorus and low blood phosphorus.
Patients with renal tubular acidosis are advised to go to regular hospitals for timely consultation and targeted treatment or therapy under the guidance of doctors.