For a long time, vulvar lesions with whitening, thickening or atrophy of the skin and mucous membranes were collectively referred to as “leukoplakia vulvae”, while those with atypical cellular hyperplasia were also diagnosed as “leukoplakia vulvae”, for the sake of consistency. In 1975, the International Society for the Study of Female Vulvar Diseases (ISSFVD) changed the name to “chronic female genital dystrophy”. “In 1975, the International Society for the Study of Female Vulvar Disease changed its name to chronic vulvar dystrophy, which includes hyperplastic dystrophy, sclerosing mossy dystrophy and mixed dystrophy. In recent years, a large number of studies and investigations at home and abroad have found that the cancer rate of this disease is not high, and most of them are non-cancerous pre-cancerous lesions, and only 3%-5% of them may develop into cancer. The exact etiology of vulvar leukoplakia is still unclear. In addition to systemic factors, localized moisture and heat stimulation of the vulva can also lead to vulvar leukoplakia.