Vulvar leukoplakia is a type of gynecological disease vulvar leukoplakia. It is a lesion in which the skin and mucosal tissues of the vulva undergo pigmentary changes and degeneration, which is a non-specific disease and can only be relieved by topical ointment. Vulvar leukoplakia refers to the appearance of limited or diffuse white patches on the skin of a woman’s pubic area, some of which may show symptoms such as vulvar itching and atrophy. Currently there is no specific treatment. Most of the treatment is a combination of Chinese and Western medicine. Hydrocortisone ointment can be applied to the vulva to stop itching, or testosterone propionate cod liver oil ointment. Traditional Chinese medicine mostly combines with the overall situation of the patient, dialectical analysis, giving Chinese medicine external washing or homemade Chinese medicine ointment external application. Microwave, laser irradiation therapy can also be used, the effect is also possible. At the same time, regular gynecological examination, leukorrhea routine, etc., found lesions, timely treatment. In addition, we should pay attention to keep the vulva clean, dry and hygienic, wear breathable and loose underwear, change underwear frequently; eat a light diet, avoid spicy and stimulating food; increase physical exercise to increase the body’s immunity. When vulvar leukoplakia is diagnosed, it should be treated with topical ointment as prescribed by the doctor in regular hospitals, and be reviewed regularly to prevent it from causing other diseases.