Microscopic lesion nephrotic syndrome is a lifelong disease. This type of nephrotic syndrome is well treated by hormonal therapy, and a small number of people can achieve clinical cure with treatment, but it is easy to relapse. Microscopic lesion is one of the causes of nephrotic syndrome, with damage to the kidney as the main symptom, in the treatment of nephrotic syndrome, we seldom say whether it can be cured or not, but whether it can be relieved or not, that is to say, this is a long-lasting disease, it is difficult to cure directly, and the purpose of the treatment of nephrotic disease is to slow down the deterioration of the disease as much as possible. Microscopic lesion nephrotic syndrome is more sensitive to hormone, so hormone treatment is more effective, but it will be easy to relapse, so it can be said that it is a lifelong disease. Microscopic lesion nephrotic syndrome should be treated actively to prolong the life time and improve the quality of life.