For patients with chronic liver diseases such as viral hepatitis and fatty liver, it is very important to prevent the process of liver fibrosis – cirrhosis – liver cancer. 1. Cordyceps preparation: The active ingredient of Cordyceps is Cordyceps head cell mycelium, which is an anti-aging herbal medicine that has the function of protecting heart and liver. It can inhibit the deposition of total collagen and type I and III collagen in the liver, so that the collagen already formed can be dissolved and absorbed again. Heart and Liver Capsules belong to this category and the dosage is 4-6 capsules (1.0-1.5g) each time, 3 times a day for 3-6 months. Compound turtle shell soft liver tablet has a significant inhibitory effect on the proliferation of lipid storage cells that promote fibrosis, and can block or delay the process of liver fibrosis. The dosage is 4 tablets each time, 3 times a day, for 3-6 months, and the duration can be extended if effective. 2.Compound salvia preparation: clinically, after taking compound salvia preparation for post-hepatitis cirrhosis patients, the portal vein pressure and splenic vein pressure decrease, and the spleen has a certain degree of retraction, which can mainly lead to a significant decrease in the test index of type III pre-collagen peptide (PIII) and laminin (LN). 3.Peach kernel preparation: Shanghai Institute of Traditional Chinese Medicine used this preparation to treat patients with cirrhosis, and those who used it for more than 6 months, the indexes of hyaluronidase (HA) and laminin (LN) in laboratory tests decreased, serum albumin could rise, and the level of cellular immunity improved. 4.Hanfangji A: It is the extract of Chinese medicine Hanfangji, each dosage is 50mg, 3 times a day, half a month is a course of treatment, it can make the serum type III pre-collagen peptide and hyaluronidase (HA) decrease than before treatment, and the degree of liver tissue fibrosis is reduced. 5.Colchicine: It can reduce the synthesis of collagen, treat chronic hepatitis and prevent the development of cirrhosis, with an efficiency of 66%. The dosage is 0.5mg per time, taken twice a day, 5 times a week, and the course of treatment is at least 3 months.