Although the overall manifestation of depression is persistent depressed mood, unhappiness, loss of interest, decreased energy, negative pessimism, insomnia and poor nana. But there are also many different clinical manifestations, the author in clinical treatment, according to the different clinical subtypes are divided into 6 categories, respectively, to introduce, give identification, in the clinical existence of different treatment responses, if better distinguished, the treatment effect should be more prominent! Introduced as follows: 1., with depressed mood as the core of the performance of this category of patients, the main complaint is poor mood, happy not up, unexplained fretfulness, reduced cheerfulness or decreased interest, in a word, is not happy, some patients can also barely work or take care of household chores, but the inner negative emotions are also ready to feel tormented. Many depressed patients come to see the doctor mainly because they are anxious and restless, and even restless, and they can’t do anything to their hearts, and they often lose sight of one thing and another, and they often get angry with their families or colleagues for no reason, making interpersonal relationships tense and unpleasant, but they can’t control it, and the more they want to be quiet, the more they can’t. Older patients have such symptoms, and in serious cases, they are more impulsive and even suicidal, which should not be taken seriously. 3.Somatic symptoms as a manifestation of these patients initially because of a variety of physical discomfort and seek medical treatment around, mostly wandering in the comprehensive department, such as the anterior region of the heart due to discomfort suspected of heart disease and repeatedly in the cardiology and surgery treatment, the effect is unclear, or gastrointestinal discomfort in the gastroenterology department, a number of unsuccessful examination and distress, or most of the pain for unknown reasons multi-disciplinary treatment and diagnosis, the effect is repeated, always can not be cured, the serious people have the idea of light. It is mostly seen in women above middle age. 4. The manifestation of biological rhythm change can be seen as sleep disorder and eating disorder, such as difficulty in falling asleep, easy to wake up, early awakening, poor appetite, wasting, etc. The patient’s clothing is gradually relaxed, sleep and food disturbance, very painful. Some depressed patients are inexplicably fatigued and sleepy, unable to do anything, do not want to move, and need to rest immediately if they move a little, complaining that their legs are as heavy as lead, their limbs are stiff, and they often want to lie in bed. 6, with cognitive symptoms as the main manifestation Some depressed friends always feel attention and memory problems, unable to concentrate and pay attention, often lose things, forgetfulness, even can not remember the necessary things in daily life, such as grocery shopping, payment of utility bills date, calculation ability, etc. is significantly affected, very distressed. In some cases, despite the improvement of emotional symptoms after treatment, attention and memory, work ability just can’t return to the pre-morbid level. This kind of depression with impaired cognitive function as a precursor manifestation is more common in elderly patients and needs close attention to differentiate it from dementia. Therefore, when you find out you have depression, you also need your doctor to help you know which subtype of depression you are, and the treatment strategy is different, so that you can develop a treatment plan suitable for you according to the local conditions, in order to carry out the treatment according to the local conditions and finally achieve recovery!