Liver and gallbladder, liver and gallbladder, liver and gallbladder, chivalry and righteousness are words that can often be heard, and these words reflect the close relationship between liver and gallbladder. From the human anatomy, liver and gallbladder are the two closest organs, the liver and gallbladder arteries are connected, the ducts are connected, the gallbladder is attached to the liver for survival, and the bile secreted by the liver needs the gallbladder for concentration and excretion. The bile secreted by the liver needs to be concentrated and excreted by the gallbladder. When the liver is sick, the gallbladder can be involved, and when the gallbladder is sick, the liver can be affected. The liver and the gallbladder are structurally inseparable, functionally coordinated and mutually useful, and pathologically influenced by each other. But why is there so much general knowledge about the liver in medical science and so little about the gallbladder? It is because most doctors consider gallbladder disease as an ancient disease and a familiar one. In fact, gallbladder disease is also increasing in incidence with the rising standard of living and the increasing pressure of survival, and also with the changing lifestyle making the condition more and more complicated, so today gallbladder disease is also one of the modern life diseases to pay more attention to ensure the health of one side. The gallbladder has the important function of concentrating, storing and excreting bile, which has the function of helping fat digestion and absorption. Common gallbladder diseases include gallstones, cholecystitis and gallbladder polyp-like changes. Gallstones can occur in the gallbladder, bile ducts, hepatic ducts and intrahepatic bile ducts and are composed of cholesterol stones, bilirubin stones and mixed stones. The etiology of gallstones is complex and is still being explored. It is generally believed to be related to bile stasis due to neurological disorders, metabolic disorders of bile and cholesterol, and biliary tract infections. According to clinical observation, women, post-middle-aged, high sugar, high fat, high protein diet, refusal of breakfast, obese, biliary parasites, diabetes mellitus, cirrhosis and hemolytic disease, most of the stomach removed and part of the colon removed, and parents with this disease are susceptible. Simple gallstones may be asymptomatic or may cause only mild digestive discomfort. However, if the stone is embedded and the bile duct is obstructed or if it is infected, it may cause biliary colic and cholecystitis with paroxysmal colic or persistent dull pain in the right upper abdomen, fever, chills, nausea, vomiting and jaundice. In severe cases, it can be complicated by gallbladder perforation, peribiliary abscess, peritonitis, pancreatitis, myocardial infarction and other critical illnesses that are life-threatening. Even static gallstones can induce gallbladder cancer due to the long-term mechanical stimulation of the gallbladder wall by stones. The older the patient is, the higher the incidence and attack rate of gallstones, and there are no gallstones that do not attack for life. Asymptomatic gallbladder stones are not harmless to human body, but static gallstones are often life-threatening when there is obvious discomfort, so some scholars advocate the preventive removal of gallbladder stones to remove the stones and eliminate the complications of gallbladder cancer. This is why some scholars advocate the prophylactic removal of gallbladder stones to remove the stones and eliminate the site of gallbladder cancer. However, stones can occur not only in the gallbladder, but also in the bile ducts, so patients should also prevent gallstones after gallbladder removal. The occurrence of gallstones is closely related to the modern poor lifestyle. To prevent gallstones, we must first develop good habits, such as insisting on exercise to promote bile duct movement to facilitate bile renewal, meat and vegetables, regular meals, dietary hygiene, weight loss, avoiding alcohol, drinking water, low sugar, low fat, low cholesterol, and high fiber foods. Acute cholecystitis is mainly caused by obstruction of bile duct stones, which can lead to fever, right upper abdominal pain, nausea, vomiting and jaundice. Acute cholecystitis can be cured with active treatment. Chronic cholecystitis is also mostly caused by gallstones, and can also be caused by extended episodes of acute cholecystitis, and is also associated with cold, gas, and bacterial infection. Chronic cholecystitis herbal medicine liver and gallbladder with good effect. Polyp-like changes in the gallbladder are also clinically common, usually without obvious symptoms, and are mostly detected by ultrasound. Some polyps need dynamic observation, while others need surgical treatment. Gallbladder cancer is not uncommon nowadays. Although gallbladder cancer takes the fifth place among the malignant tumors of digestive tract, it is the first place among the malignant tumors of biliary tract. The exact cause of gallbladder cancer has not been confirmed yet, but many scholars believe that gallbladder cancer is closely related to gallstones, so active treatment of gallstones is also an important aspect of gallbladder cancer prevention. Focusing on the gallbladder and long-term prevention of gallbladder diseases, we should not forget the liver. In addition to the physiological and anatomical relationship between liver and gallbladder, there is also a close functional connection and pathological impact. Bile comes from the liver and is stored in the gallbladder. If the liver’s drainage function is normal, bile can be secreted and excreted normally. If the liver is not draining, the secretion and excretion of bile cannot be carried out normally, it will affect the digestion and absorption of fat by the spleen, stomach and small intestine and eventually cause damp-heat to develop internally, and Chinese medicine believes that damp-heat in the liver and gallbladder is the main cause of gallstones and cholecystitis, and treats draining the liver and gallbladder and clearing damp-heat in the liver and gallbladder as an important aspect of Chinese medicine for gallbladder diseases. In addition, the liver is the main drainage, the bile is the main decision, the liver and bile in the defense and elimination of certain mental stimulation, maintain and control the normal operation of qi and blood, promote and ensure the coordination between the internal organs of the relationship also has an important synergistic role, so Chinese medicine has the liver and bile together with the clinical principle of regulating the liver and bile, meaning that the treatment of liver disease to prevent liver disease does not forget the bile, bile disease to prevent bile disease does not forget the liver.