Liver failure is a serious health risk that used to occur in people with underlying chronic liver disease or hepatitis B virus carriers, but in recent years it has been occurring more often in healthy pregnant women. The main disease that used to occur in healthy pregnant women with liver failure was acute fatty liver in pregnancy, but in recent years the incidence of liver failure due to drug-induced liver damage has been gradually increasing. I often feel sorry and sad for these beautiful and happy pregnant women during the rescue and review process, because whether we medical personnel or the general public more if we can grasp a little more knowledge about this area and a little more vigilance, we may avoid a lot of bad luck and preserve many happy families. The following is a little experience that I have learned in the process of treatment or review and share with you, I hope it will help you. 1. For pregnant women over 30 weeks of gestation with personality change, loss of appetite, diarrhea, nausea and vomiting, and dark yellow urine, they should go to the hospital promptly to clarify the cause and understand the liver damage as early as possible. In the process of treating a patient, we learned that the patient had the above-mentioned condition at 32 weeks of pregnancy, but her family thought it was still a reaction to pregnancy and did not pay attention to it in time. 2, in the perinatal period there are other entrapment, such as fever, diarrhea and other conditions, inappropriate use of drugs, resulting in serious drug liver damage. Such as in last year, there is a maternal discharge to home the next day diarrhea, fever, the same day to the nearby hospital to see the emergency room, emergency physicians gave some simple antibiotics to take, the next day no improvement continued in the local hospital emergency room, the physician that the condition is not serious again to give anti-infective drugs, three days later the patient appeared obvious weakness, a sharp decrease in appetite, accompanied by nausea and urine yellow, the family attention Although the physician promptly gave the traditional symptomatic treatment, such as high jaundice index to give Simethicone, high ghrelin to give glycopyrrolate drug treatment, did not get the specialized treatment from the specialist in time, that is, did not get in the first time from the disease etiology of the disease mechanism, from the root to actively take rescue and treatment measures, perhaps In the end, the opportunity to save the disease was lost. 3, once the liver damage occurs, we should go to a hospital with strong specialization in a timely manner. After eight years of exploring the centralized treatment of liver failure, we in the Department of Critical Care Hepatitis have changed our thinking about the diagnosis and treatment of liver failure in a narrow sense and taken the lead in applying the concept of Bundles of Care in the treatment strategy of liver failure, which sets positive treatment goals for patients with complex and variable liver failure according to different pathological mechanisms and timing of disease onset and development, and designs comprehensive treatment plans around the treatment goals. At the same time, it has clear timing, target and sequential in the implementation process, and puts forward the strategy of clustering liver failure rescue and treatment, which has accumulated rich experience in more than one thousand cases of liver failure patients and achieved good clinical results. 4.The first 10 days after the occurrence of liver failure, that is, in the rising pre-liver failure, rising period, that is, the early stage of the disease, there is a golden window period, missing this opportunity will miss a good opportunity to save, timely and correct treatment at this time will greatly improve the success rate of saving. 5, the rescue and treatment of liver failure has a strong professional, some patients after the onset of the disease did not draw attention to themselves and their families, delaying the time of treatment, there are also primary medical units of medical personnel do not know this kind of disease, more many hospitals know this disease, but do not understand the correct measures and methods of treatment of this disease, will lead to the danger of this kind of patients, so I would like to call on all walks of life medical personnel, the general public must I would like to call on all medical professionals and the general public to pay attention to this disease and to contact a specialist as soon as possible to seek medical attention from a specialized medical unit once the aura signs of this disease are detected. In foreign countries, hepatology is part of the gastroenterology department, but in China the traditional sense of gastroenterology focuses on gastrointestinal diseases, and its treatment of cirrhosis is mainly for the complications of cirrhosis, such as gastrointestinal bleeding, and does not include liver disease itself. The rapid medical career in recent years, for liver disease has formed a strong discipline of liver disease, really as the discipline of cardiology, has a strong specialization, do not ignore this point!