Liver failure can cause the following symptoms: 1. neuropsychiatric symptoms, such as irritability, reversal of day and night sleep, drowsiness and even coma; 2. severe gastrointestinal symptoms, such as anorexia, nausea and vomiting, abdominal distension; 3. coagulation dysfunction, patients can be found to have prolonged prothrombin time and prothrombin activity less than 40% after testing; 4. progressive deepening of jaundice, total bilirubin can exceed 171μmol/L or a daily rise in bilirubin greater than 17.1 μmol/L; 5. ascites; 6. multi-organ dysfunction. In addition, liver failure is an acute liver injury caused by multiple causes, which can subsequently lead to abnormalities in the synthesis, detoxification, excretion and biotransformation functions of the liver.