The first choice of syphilis treatment in the clinic is long-acting penicillin, the most commonly used in the clinic is benzathine penicillin, benzathine penicillin is a weekly injection of 2.4 million units, once a week, 3 times for a course of treatment. The most important thing is that you can get the most out of your syphilis. The vast majority of syphilis patients need to adhere to antibiotic treatment, until the titer can be controlled below 1:4, then you can stop the drug observation. Then the patient enters a long titer observation period, usually about 3 years, and if the titer rises again during the titer observation period, the patient needs to be treated with antibiotics again. The patient can be considered cured if the titer does not increase or even gradually decreases after 3 years of observation, and neurosyphilis and cardiovascular syphilis can be excluded.