The onset of syphilis (incubation period) varies depending on the patient’s personal constitution and the number of syphilis spirochetes infected, it is a sexually transmitted disease that can infect the whole body, the pathogenic microorganism is the syphilis spirochete, the incubation period is generally 2-4 weeks, the onset of the disease varies from person to person. 1, people with better constitution: relatively good health, strong resistance, or due to a disease is taking antibiotics, resulting in syphilis spirochetes are less likely to multiply in large numbers in a short period of time. The syphilis spirochetes are less likely to multiply in large numbers within a short period of time, and the onset of the disease may be relatively late, and it may take months or even years from the time of contracting the disease to gradually appear syphilis rash or neurological symptoms and other manifestations, which can only be found to carry syphilis antibodies after a blood test; 2. People with a slightly poorer constitution: the infected person has a poorer resistance and the number of syphilis spirochetes invading the body is higher, resulting in earlier skin The appearance of hard chancre such as erosion and ulceration, i.e. syphilis attack, may appear within 2-4 weeks after infection with syphilis spirochetes. Syphilis is usually contracted after impure sexual intercourse and the first site of lesion is usually the genital organs. Therefore, once you find out that you may be infected with syphilis, you should immediately go to a regular hospital and actively cooperate with the treatment. In addition to using medication, patients should pay attention to a healthy diet and exercise to improve their resistance and try to avoid recurrence.