1, early detection and early treatment, adhere to regular and adequate treatment. 2, early syphilis is highly contagious, attention should be paid to isolation treatment to avoid cross-infection. And check and treat their sexual partners to prevent retransmission and reinfection of STDs. 3, avoid sexual intercourse during treatment, contaminated underwear, bath towels and other clothing boiling disinfection, separate bathing utensils, forbidden to share bed and bath with infants and children. 4.Strict prenatal examination for pregnant women to eliminate congenital syphilis children and reduce fetal mortality. 5, regular outpatient review, syphilis should be followed up for 2-3 years after conventional treatment, every three months in the first year, every six months in the second year, and at the end of the third year.