Hemolytic anemia is a general term for a large group of diseases in which anemia occurs due to accelerated destruction of red blood cells beyond the compensatory capacity of the bone marrow to produce red blood cells. The life span of normal red blood cells in the blood circulation is about 120 days. The dynamic balance is maintained by the continuous destruction and removal of senescent red blood cells and the continuous production and release of new red blood cells from the bone marrow. In hemolytic anemia, the survival time of red blood cells is shortened to varying degrees, with the shortest being only a few days. If the hematopoietic function of the bone marrow is normal, the compensatory hematopoietic function of the bone marrow can be increased 6 to 8 times compared to the usual one when the life span of red blood cells is shortened or destroyed for various reasons and hemolysis is increased, so that anemia can not occur. This condition is called “compensatory hemolytic disease”. If the compensatory hematopoiesis of the bone marrow is not as fast as the hemolysis, then the anemia will appear, which is called hemolytic anemia. The manifestations of hemolytic anemia are as follows: 1. manifestations of anemia: yellow face, weakness, panic, dizziness, blurred eyes, and tinnitus. 2, manifestations of red blood cell destruction: yellow sclera, deepening of urine color, the color of strong tea, vinegar, in case of paroxysmal sleep proteinuria, there is deepening of urine color after sleep, and in severe cases, the urine is soy sauce color. 3. There may be splenomegaly.