Intracranial infection is one of the more common complications in neurosurgery and one of the more serious diseases of the central nervous system. It is mostly caused by the invasion of pathogens such as bacteria, viruses, parasites, mycoplasma, chlamydia, mycobacteria and rickettsia into the central nervous system, i.e., the cranial brain, resulting in a series of symptoms, including encephalitis, meningitis and brain abscess. Symptoms of intracranial infections? The early stage of intracranial infection is usually characterized by fever, headache, vomiting, impaired consciousness, neck straightening, etc. The bacterial culture of cerebrospinal fluid may be positive, and there are many changes in cerebrospinal fluid properties and laboratory tests; severe cases may not be able to eat on their own, incontinence, persistent coma, etc. Acute cases of A. baumannii, Klebsiella pneumoniae, and Pseudomonas aeruginosa (green pus) infections are mostly manifested as purulent cerebrospinal fluid, and conventional anti-infective treatment is generally ineffective. How to diagnose intracranial infection? Diagnostic criteria for intracranial infection: 1. Clinical symptoms and signs of intracranial infection such as high fever, headache, neck tonicity, etc. 2. WBC > 0.01X109/L in cerebrospinal fluid examination, with an increase in polymorphonuclear cells as the main cause. The results of cerebrospinal fluid bacterial culture are positive. 4. There is a definite cause of infection, such as cerebrospinal fluid leakage. The diagnosis can be confirmed by having the 3rd article. If the bacterial culture of cerebrospinal fluid is negative, the rest of the articles need to be integrated. What is the treatment and cost of intracranial infection? Treatment of intracranial infections is clinically tricky. If the intracranial infection is caused by Gram-positive cocci, it is relatively good to be treated, but due to the application of many high-level antibiotics and even clinical abuse in recent years, the intracranial infection which is quite good to be treated has developed into a drug-resistant bacterial infection which is difficult to be cured. Like Acinetobacter baumannii, Klebsiella pneumoniae, Pseudomonas aeruginosa and so on belong to the drug-resistant superbacteria, most of the general antibiotic treatment is ineffective and even delays the treatment. So at this point, it is very important to choose a correct method of treatment in time. At present, there is a whole set of special treatment technologies for cerebrospinal fluid specialties, which can achieve satisfactory results for various pathogenic bacterial infections by using a unique approach to precise anti-infection treatment, purification of cerebrospinal fluid, and restoration of the ventricular wall. So is the cost of treating intracranial infections high? The cost of treatment is not high, and after reimbursement through medical insurance, the part borne by individuals is not much.