Patient: Examination and laboratory tests: baby had 2 cramps after fever subsided, CT was done with no problem, doctor told to do lumbar puncture without promise, appointment for EEG on the 20th. Treatment: whether MRI can replace lumbar puncture to determine if intracranial infection. Medical history: My grandmother and father had cramps when they had a high fever, but my baby had cramps twice (on the same day) after a high fever, is there a possibility of heredity? My grandmother and father had cramps when they had high fever, but my grandmother was in a coma for 2 days once when she was a child, and my father had high fever twice when he was a child and had cramps on both occasions. Can MRI help diagnose intracranial infection without lumbar puncture? DZ: Lumbar puncture is the most accurate way to diagnose intracranial infections, because it is an invasive test (although most of them do not have any sequelae) and is not easily accepted by parents. MRI is not a substitute for lumbar puncture to diagnose intracranial infections, but it can rule out more serious intracranial infections. If your child’s father and grandmother both had a history of convulsions after a high fever, it is possible that the child had a similar condition, which we call febrile convulsions, but because he had two convulsions, we call them complex febrile convulsions. However, it needs to be determined with the help of EEG after intracranial infection has been ruled out. Patient: Okay, thank you, doctor. Then I would like to ask the baby to go home and observe for 3 days, the situation is all good, appetite and spirit are restored, so is there still a possibility of intracranial infection? Dr. Zhao: It is less likely. Patient: Thank you so much, doctor. We’ll go over for an EEG on the 30th. We will see you again then. Thank you! Dr. Zhao: You can come to my clinic.