For flu-like syndrome, bone marrow suppression, loss of appetite, weight loss, diarrhea, rash, hair loss, mental abnormalities, thyroid disease and aseptic inflammation at the injection site, etc. 1, flu-like syndrome: manifested as fever, chills, headache, muscle aches, weakness, etc., can be injected at bedtime interferon, or after the injection of interferon to take non-steroidal anti-inflammatory analgesics to reduce flu-like symptoms. Such symptoms gradually decrease or disappear with the prolongation of the treatment course. The Third Hospital of Sun Yat-sen University, Department of Infectious Diseases, Lin Chaoshuang 2, bone marrow suppression: transient bone marrow suppression is mainly manifested as a decrease in peripheral blood leukocytes and platelets. If the absolute number of neutrophils ≤ 0, 75 × 109/L, platelets.