With the improvement of living standard, people suffering from liver diseases are increasing day by day, however, liver cancer is one of them, which is mainly caused by some bad factors in people’s life and is very harmful to human body. I believe many people are familiar with liver cancer because we all know how harmful this disease is to human body, and if the patient does not take effective treatment, when the disease develops to advanced stage, it will lead to many complications and even death. Therefore, we must pay attention to this disease and take some relevant treatment measures. Usually, when liver cancer develops to advanced stage, it presents a lot of pain in the patient’s body, so we should pay attention to the advanced liver cancer. First, upper gastrointestinal bleeding, liver cancer is a serious disease which usually leads to upper gastrointestinal bleeding when the disease is advanced, mainly because of portal hypertension in the patient’s body. Liver coma is one of the most common complications of advanced liver cancer, and the patient’s condition is already very serious at this time. In early stage of liver coma, the patient usually shows upside down sleep and irritability. Thirdly, infection is also a common phenomenon in advanced liver cancer disease. It is mainly due to the rapid decline of immunity in patients’ body and the inability of all organs to resist the invasion of germs, therefore, infection will occur, usually patients will show some symptoms such as fever, abdominal pain and liver ascites, which will cause serious harm to patients. In conclusion, the symptoms of liver cancer are very obvious and the degree of damage caused to the patient is also very great, so we have to take some targeted treatment measures, so what are the methods that can usually play a therapeutic role in the treatment of advanced liver cancer, such as radiation therapy, chemotherapy, immunotherapy, alcohol-free injection therapy, Chinese herbal medicine therapy and other treatments. And although these treatments can not cure the disease completely, but for the control of the patient’s condition is a great help, but also to improve the chances of survival of patients.