There are many kinds of drugs that can prolong the time of intercourse, it is recommended to consult a professional doctor in urology or male medicine and follow the medical advice according to the specific situation. It is generally believed that psychological or mental factors are important factors leading to premature ejaculation. Patients can consult a psychologist for psychological guidance or take tricyclic antidepressants, such as chlorpromazine, as prescribed by the doctor, which can help prolong the time of intercourse to a certain extent. In addition, the central nervous system 5-hydroxytryptamine neurotransmitter disorder and high penile head sensitivity are also important causes of premature ejaculation in men. For such patients, local topical anesthetics for the head of the penis or oral selective 5-hydroxytryptamine reuptake inhibitors can be used as prescribed by the doctor to properly prolong the time of intercourse. In short, premature ejaculation patients often produce anxiety, so maintain an optimistic state of mind is very beneficial to the disease, do not avoid the disease. In addition, patients should actively learn about related knowledge, treat premature ejaculation correctly, and carry out treatment under the guidance of doctors and with the cooperation of their partners.