What are the hormonal drugs for gout? Can hormones be used during acute joint severity of gout? Hormones are not used during the interval of high uric acid or gout, but they can be used during an acute joint attack of gout. In addition to colchicine and non-steroidal anti-inflammatory drugs, hormones can also be used during acute gouty arthritis attacks. In the process of using hormones, there are oral hormones, intravenous hormones and topical hormones. According to the patient’s condition, if the patient has no problems with oral intake, then oral hormones can be used, including prednisolone acetate, methylprednisolone, and dexamethasone tablets. If the patient has problems with oral intake, he can use intramuscular hormone drugs. If intramuscular injection is also contraindicated, or during hospitalization, he can use intravenous hormone drugs, including hydrocortisone, dexamethasone, and methylprednisolone injection. For local redness, swelling and pain, topical hormonal creams can also be used.