Depression that does not want to do anything is a very common manifestation of depression. This is because the core symptoms of depression are low mood, diminished interest, and energy fatigue, accompanied by a decline in ability. When interest is diminished, there is a reluctance to do all the things that you used to love to do. At the same time, energy loss is accompanied by reduced ability to perform tasks that used to be possible, but now cannot be done. This is related to the lack of the neurotransmitter pentraxin in the brain, and when pentraxin is disrupted in a certain brain area, the above symptoms will occur. A number of scholars believe that this is a manifestation of the reduced positive capacity of depression, which is more complicated and difficult to treat. Clinically, in addition to the now commonly used SSRI drugs, such as sertraline and citalopram, etc. In addition to medication, psychotherapy is also needed to improve the patient’s symptoms by correcting the patient’s cognition. Behavioral therapy in psychotherapy is also very important to encourage patients to go out for more exercise and participate in social activities so as to restore their social functions. Therefore, depressed patients, who only show improvement in symptoms of depressed mood, can only indicate that the symptoms are cured, but do not reach full social recovery; only when they return to their previous working ability will they reach true healing.