Otosclerosis 1. Deafness: Progressive hearing loss in both ears or one ear is the main symptom of the disease. Self-perceived symptoms or examination findings. (Must have) 2. Tinnitus: About 20%-80% of patients have tinnitus. Tinnitus is mostly low-frequency, persistent or intermittent, and high-frequency tinnitus may appear in later stages. （3. Wechsler’s mishearing phenomenon: Patients have difficulty in distinguishing speech in the general environment, but their ability to hear in a noisy environment is improved, which is called Wechsler’s mishearing. （4. Vertigo: A few patients have transient mild vertigo during head movement. (Rarely) 5. Family history. (May have) SLE screening Arthralgia, joint swelling and pain, recurrent mouth ulcers (more than 3 per year), malaise, unprovoked fever, photosensitivity (UV sensitivity), rash (especially pteroidal erythema on the face), physical examination reveals decreased blood count in any of the three lines, proteinuria. Further screening for SLE is done with any of these conditions, both blood tests (antinuclear antibodies, rheumatology 17, immune 5). Hematoporphyria: Unexplained abdominal pain, menstrual dysfunction, especially peripheral nerve symptoms, localized muscle weakness flaccid paralysis, etc., presence of large amounts of ALA and PBG. urine gradually turns dark red or even black. Rheumatic chorea, also known as micro chorea, often occurs after streptococcal infection and is a neurological symptom of acute rheumatic fever. The lesions mainly affect the cerebral cortex, basal ganglia and cerebellum, and are caused by extrapyramidal dysfunction. The disease is characterized by rapid choreiform involuntary movements of the face, hands and feet, with decreased muscle tone, reduced muscle strength and psychiatric symptoms. Occasionally, it occurs in adult women. (1) Blurred vision; (2) Sudden onset of slurred speech, difficulty in spitting out words, inability to speak, as if cotton had been stuffed into the mouth; or inability to understand the meaning of other people’s speech; (3) An unbearable limited headache, or a headache that is completely different from the usual form, such as a full headache to a limited headache, intermittent headache to a continuous attack, or accompanied by nausea (4) Suddenly feel spinning, shaking, unstable, or even fainting. (4) Sudden spinning, swaying, unsteadiness, or even fainting. This often occurs together with double vision (diplopia) and tinnitus; sudden forgetfulness of all recent events. (5) Sudden numbness, weakness, unstable holding, falling of dishes, drooping of the corners of the mouth, drooling on one side of the face or upper and lower limbs. (6) Sleep disorders. (7) Sudden onset of personality, behavior and intelligence abnormalities, inattention, impaired judgment and understanding, lack of memory, especially near memory impairment, silence, emotional instability, depression, aloofness, indifferent expression, irritability, etc. (8) Sudden onset of unconsciousness, inability to respond to calls, convulsions, and urinary incontinence.