Ms. Wu, 24, is now a sales manager of a company, usually busy, often staying up late and working under great pressure. Although the company’s treatment is good, but its happiness index is extremely low. Outwardly beautiful, she suffers from “menstrual disease” all year round. The amount of menstruation is very small, sometimes sitting there, cold will be a false sweat. In recent months, the menstruation simply does not come. The doctor’s examination at the hospital revealed that it was premature ovarian failure. The clinical manifestation is accompanied by different degrees of hot flashes and sweating, vaginal dryness, decreased libido and other pre- and post-menopausal symptoms, making the patient decline before her age, bringing great pain to her physical and mental health and married life. In recent years, some data show that the onset of menopause in women is developing at a younger age, with many young women experiencing menopause, palpitations, irritability and insomnia. Premature ovarian failure is harmful. After the ovarian function declines, the level of estrogen and progesterone in the blood decreases, bone loss accelerates, and patients are prone to osteoporosis and even fractures. Studies have found that patients with premature ovarian failure have a higher incidence of cardiovascular disease than women of the same age. Some studies have also found that patients with premature ovarian failure may develop Alzheimer’s disease earlier. To date, the pathogenesis of premature ovarian failure is unknown and may be due to a congenital reduction in the number of eggs, accelerated atresia of normal follicles, and premature follicular depletion due to destruction of eggs by different mechanisms after birth. The main causes of premature ovarian failure are autoimmune abnormalities, the most common of which are thyroid disorders; chromosomal abnormalities or other genetic factors, such as Turner syndrome with X chromosome abnormalities; viral infections, commonly mumps with ovarian inflammation in early childhood, which disrupt ovarian function and make the ovaries insensitive to pituitary gonadotropin stimulation and do not respond as they should. In addition, there is also a close relationship with surgery or drugs or radiation damage. The treatment of premature ovarian failure Nowadays, beauty parlors promote ovarian maintenance, but in fact ovarian maintenance is not based on science. It is not possible to reverse premature ovarian failure by taking care of your ovaries. The ovaries are located in the lower abdomen on both sides of the uterus in the pelvis, one on each side, connected to the uterus by ligaments, and are the most important reproductive organ of women, as well as the main reproductive endocrine gland. It has a dedicated blood supply, the ovarian artery, which is a branch of the uterine artery. In addition to its own secretory regulation, the ovary is mainly controlled by the pituitary gland, which directly determines whether it ovulates normally or not. The pituitary gland is controlled by the hypothalamus, which in turn is controlled by the cerebral cortex, which is mainly controlled by the person’s mood. Moreover, the synthesis of estrogen is not the work of one organ, the ovary, but of an integrated system (medically called the “endocrine axis”). In other words, the hypothalamus, pituitary gland and ovaries must work together in unison to form a complete and coordinated neuroendocrine system in order to release sufficient amount of estrogen from the ovaries. Such a complex and wonderful physiological process can’t be solved by simply taking care of one organ? It is medically proven that the way to stimulate the pituitary gland so that the ovaries can secrete hormones is to use hormones, and the use of hormones requires the guidance of a doctor. If the dose of hormones is too much, or if the woman herself has gynecological diseases, such as breast cancer, the use of hormones is likely to trigger or aggravate the disease. For patients who require fertility, a small percentage of patients can resume ovulation and conceive naturally during hormone replacement therapy. Most patients need egg donation for in vitro fertilization-embryo transfer to obtain pregnancy. In addition to the above treatments, a scientific lifestyle is also important. Patients should stop smoking, get out of a bad living environment and face the disease with a positive attitude. Patients should also take adequate calcium and vitamin D intake and exercise. White collar women under pressure should learn to self-regulate their emotions, treat the psychological conflicts that occur correctly, and go out to travel and chat with friends to vent their bad emotions in time. Reasonable rhythm of life, to achieve regular living, sleep, work and rest, and develop a wide range of hobbies.