1.No history of alcohol consumption or alcohol consumption equivalent to 140 grams of ethanol per week for men and 70 grams for women; 2.Exclusion of specific diseases that can lead to fatty liver such as viral hepatitis, drug-related liver disease, total parenteral nutrition, hepatomegaly, etc. 3.In addition to the clinical manifestations of the primary disease, there are non-specific symptoms and signs such as weakness, dyspepsia, vague pain in the liver area, and hepatosplenomegaly. 4, There may be metabolic syndrome such as overweight/visceral obesity, increased fasting glucose, dyslipidemia, hypertension, etc. 5.Serum aminotransferase and glutamyl transpeptidase levels may be mildly to moderately increased (less than 5 times the upper limit of normal value), usually with a predominant increase in alanine aminotransferase (commonly known as “GPT” in the past). 6.Liver imaging is consistent with the diagnostic imaging criteria of diffuse fatty liver. 7.Histological changes on liver biopsy are consistent with the diagnostic criteria of fatty liver disease. The pathological diagnostic criteria of fatty liver disease. Fatty liver is diagnosed when any of the above items 1-5 and 6 or 7 are present. Here it is worth mentioning the calculation method and determination criteria of BMI (i.e. body mass index), BMI=weight (kg)/[height (m)]2. For Asian adults, BMI≥23kg/m2 indicates overweight, BMI≥25kg/m2 indicates mild obesity, and BMI≥30kg/m2 indicates severe obesity. Central obesity is defined as waist circumference ≥ 90 cm for men and ≥ 80 cm for women. After developing fatty liver, its intervention and treatment should emphasize comprehensive treatment, where patients must change their lifestyle, diet, exercise, abstain from alcohol and smoking, as well as control primary diseases (e.g. hypertension, diabetes and hyperlipidemia). In high-risk groups who do not recover sufficiently after adequate lifestyle treatment or who have combined cardiovascular disease, treatment with medications, including lipid regulation, blood pressure lowering and improvement of insulin resistance and blood glucose control, is required.