2014 International Standard Scoring System for Leukoaraiosis: a score of ≥4 suggests a diagnosis of leukoaraiosis
Signs/symptoms
Score
Eye damage
2
Genital ulcers
2
Oral ulcers
2
Skin damage
1
Neurological manifestations
1
Vascular manifestations
1
Positive acupuncture test
1*
* Needle prick test was non-required and was not included in the initial scoring system. However, if a needle prick test was performed and the result was positive, an additional 1 point was added.
Sensitivity and specificity of ICBD were 93.9% and 92.1%, respectively