Leukoaraiosis (leukoaraiosis, leukoaraiosis syndrome, Behcet’s syndrome, Behcet’sdisease) is a rare disease, difficult to diagnose, and a systemic vasculitis-like disease with multiple organ damage. In 2013, the Journal of the European Society of Dermatology and Venereology published: International Standard Scoring System for Behcet’s Disease According to the scoring of the symptoms and signs of Behcet’s disease, the following scores can be diagnosed when the total sum of the scores reaches 4, and the diagnostic sensitivity of this criterion is 93.9%, and the specificity is 92.1%. Yao Blood Ming, Department of Rheumatology and Immunology, The Second Affiliated Hospital of Guiyang Traditional Chinese Medicine 1, Eye lesions: 2 points 2, Genital ulcers: 2 points 3, Oral ulcers: 2 points 4, Skin damage: 1 point 5, Neurological damage: 1 point 6, Vascular manifestations: 1 point 7, Positive pinprick reaction 1* points *The pinprick reaction test is optional, and the scoring system would not otherwise have included a pinprick reaction test. However, if the pinprick reaction is positive, the score can be increased by 1 point. Self-diagnosis of leukoaraiosis Primary symptoms: 1. recurrent oral ulcers; multiple genital ulcers; 2. eye damage: may include conjunctivitis, iridocyclitis, uveitis, and optic neuritis; 3. various types of skin damage: may include erythema nodosum, or erythema multiforme, folliculitis-like or acne-like rashes and subcutaneous thrombophlebitis. Secondary symptoms: 1. arthralgia or arthritis, muscle aches and pains; low, recurrent or intermittent fever; 2. peptic ulcers; vascular and cardiac symptoms; neurologic symptoms. The presence of three or more (including three) major symptoms can be diagnosed as complete type of leukoaraiosis; two major symptoms plus two secondary symptoms can be diagnosed as incomplete type of leukoaraiosis, of which oral ulcers are a must; the mere presence of two major symptoms is a suspicious type.