In the clinical treatment of chronic nephritis drugs include the following: first, drugs to control hypertension, clinically recognized angiotensin-converting enzyme inhibitors and angiotensin II receptor antagonists have the renal protective effect of reducing blood pressure in patients with chronic nephritis, reducing the level of urinary protein in patients with chronic nephritis, and delaying the deterioration of renal function in patients with chronic nephritis. In addition, if necessary, diuretic drugs can be used in combination, such as thiazide diuretics and tab diuretics, etc. Calcium channel blockers can also be used to control the blood pressure level of patients. Second, reduce urinary protein drugs, some studies have confirmed that the application of ACEI and ARB drugs can reduce urinary protein in patients with chronic nephritis, and its therapeutic effect does not rely solely on the role of antihypertensive. Third, anticoagulation and anti-platelet drugs, for some types of nephritis, anticoagulant drugs and anti-platelet drugs have a certain role in stabilizing kidney function and reducing the pathological damage to the kidneys. Fourth, lipid-regulating drugs, it is recommended that patients can apply statin lipid-regulating drugs for treatment under the guidance of a doctor. Fifth, the application of glucocorticoids and cytotoxic drugs, if chronic nephritis patients with kidney pathology puncture results suggest that active lesions are predominant, and accompanied by a large amount of urine protein, should be actively treated. If there are no contraindications to the use of drugs, you can choose to apply glucocorticoids or combine the application of some other cytotoxic drugs for treatment.