A person who is in a state of chronic sadness may be suffering from depression. Depression is a common emotional disorder and the disease itself does not affect life expectancy, but if left untreated, the patient has a higher likelihood of being at risk and may be affected during survival. If patients are in a long-term sad state, depressive symptoms are recurrent for a long time, and they do not receive scientific and regular treatment, the factors that affect patients’ lives will become more and more serious, and the common ones are as follows: 1. If patients are severely depressed, they may die at any time from suicide or self-injury or self-harm. 2. Depression may lead to depressive malaise, refusal to eat, etc. Patients may suffer from malnutrition, organ failure and death.3. Patients may have complications with physical diseases such as diabetes, hypothyroidism, hyperthyroidism, or even cancer, which may affect life expectancy. However, if patients can receive regular treatment and regular review, their lives are basically unaffected. Once found to suffer from depression, patients should go to the psychiatric department of the regular hospital as early as possible and receive timely antidepressant treatment. Generally, 2-4 weeks of medication will have obvious effects, and the fastest will be clinically cured after 3-6 months of treatment, and the risk of suicide and somatic diseases will disappear.