Chinese medicine and Western medicine mixed phenomenon is very common, hate sickness to eat medicine, want to get better faster, several drugs together, although a proprietary Chinese medicine itself no obvious toxic side effects, but inevitably with other drugs with the chemical reaction, resulting in toxic substances, so, Chinese and Western medicines together, must pay attention to the role of each other, do not understand try not to combine the application of Chinese and Western medicines. Recently, the number of patients with kidney damage has increased significantly, and almost the entire community is looking for the killer. What “gentian diarrhea liver pill”, what “six gods pill” are the murderer, are to withdraw from the drug shelves. Recently, even “Guanxin Suhe Pill” has become the culprit of “aristolochic acid nephropathy”. If you look through the published information, you will find that Guanxin Suhe pill is not a drug containing aristolochic acid, it is Guanxin Suhe pill and western medicine isoamyl nitrite used together, can generate toxic precipitates containing mercury ions, which cause kidney function damage over time. There are many other examples like this, and here are some common Chinese and Western medicines that can be easily mixed to draw your attention to them: the use of mother-of-pearl and western medicine aminophylline together can cause poisoning; the use of Xiaohuoludan, Xianglian Pill, Chuanbei Loquatro with western medicine atropine, caffeine, 654-2 will enhance the toxicity of alkaloids; the use of Cinnabar Tranquilizer Pill with western medicine tribromine and ferrous sulfate can generate mercury bromide, mercury sulfide and other toxic substances. The combination of Hawthorn, Plum, Schisandra, etc. with western medicine sulfa is likely to cause urinary closure or hematuria; the combination of human and western medicine luminal, chloral hydrate and other sedative and antispasmodic drugs can strengthen the inhibitory effect on the central nervous system, serious enough to be fatal. The combination of Chinese patent medicine Liu Shen Wan, Yi Xin Dan and western medicine cardioplegia, quinidine can lead to cardiac arrest; the combination of Chinese patent medicine snake bile Chuan Bei liquid and western medicine morphine, dulcolax, codeine can lead to respiratory failure, the consequences are very serious. Lastly, improper use of Chinese medicines containing mercury, stellaria, aconite and toadstool can indeed cause significant toxic side effects, but these medicines are toxic in themselves and are clearly documented in classical Chinese medicine books, and if used wisely, they can also lead to miraculous cures for many difficult diseases. The key is still to use them under the guidance of TCM theory. Many of the toxic side effects can be significantly minimized if prevention is done in conjunction with clinical drug monitoring methods.