Gout is known as “the king of pain, the king of pain”, this disease will bring severe pain in the joints when the attack, but in the past, only people who eat and drink as much as the “king” can get this disease. With the improvement of people’s living standard and better diet, the intake of high purine food (including high protein food that can be easily metabolized to produce purine) is increasing, and uric acid is the metabolic product of purine, and excessive intake of purine will lead to the increase of uric acid. As a result, the number of patients with hyperuricemia (blood test uric acid above 420 μmol/L in men and above 360 μmol/L in women) is increasing day by day. High concentrations of uric acid precipitate urate crystals, which can be deposited in various parts of the body, most often in the joints of the hands and feet, and can cause gout. According to statistics, about 10% of patients with hyperuricemia will develop gout. To prevent the recurrence of gout, it is necessary to catch the “intermittent period”: gout is divided into an attack period and an intermittent period. Patients with attacks often have red, swollen and painful finger (toe) joints, and need to use pain medication to relieve the symptoms, which can be relieved in about 3-5 days; while in the intermittent period, patients do not have uncomfortable symptoms, so the best way to prevent gout attacks is to control uric acid and avoid hyperuricemia by taking medication and eating a reasonable diet. Patients can avoid the recurrence of gout by controlling uric acid to 300 μmol/L during the intermittent gout period. However, if the patient neglects to take medication and continues to eat a high purine diet to keep uric acid high, not only is gout likely to recur, but hyperuricemia can also cause chronic diseases such as hypertension, gouty nephropathy, and even gouty kidney stones, which can seriously endanger human health. The former can accelerate the excretion of uric acid, while the latter can reduce the synthesis of uric acid in the body, both of which can reduce the purpose of uric acid in the body. However, it is important to note that patients with hyperuricemia do not need to take medication prematurely, but only need to control it through diet. If the patient does not have risk factors such as hypertension and kidney disease, he can take medication above 540 μmol/L uric acid; if he has these chronic diseases, he should start taking medication above 480 μmol/L. Treatment of hyperuricemia is about slow control. If uric acid is excreted too quickly, it may cause a sudden increase in uric acid concentration in the blood and may also dissolve uric acid crystals deposited in other parts of the body, which may instead cause gout. It is especially important to note that if a patient has an acute attack of gout without medication, he or she should not take these two drugs, as the blood uric acid will further increase after taking the drugs, exacerbating the pain; likewise, patients with kidney stones are not recommended to take the drugs, as the elevated uric acid may precipitate in the kidney, exacerbating the symptoms of stones. Low purine diet to effectively reduce uric acid concentration: Whether or not you take medication, a healthy diet is very important to reduce uric acid concentration and prevent gout attacks. Gout patients should drink 2000-2500ml of water daily to increase uric acid excretion; strictly control the intake of high purine food, such as soy products (tofu, soy milk), lean meat, animal offal, fish, seafood, mushrooms, etc.; special attention should be paid to beer, which contains a large amount of purine itself, and alcohol also promotes the synthesis of uric acid and reduces the excretion effect, so it should not be consumed; vegetables, fruits, rice and noodles contain low purine and can be safely consumed. Vegetables, fruits, rice and noodles are low in purines and can be eaten with no worries. The vitamin C contained in vegetables and fruits also has the effect of lowering uric acid; dairy products are low in purines and can supplement the daily protein required.