In our clinic, there are many factors that cause headache, and there are several causes as follows: 1. Infection: Febrile diseases caused by cranial infections or acute infections in other body systems. Cranial infections that often cause headaches such as meningitis, meningoencephalitis, encephalitis, brain abscess, intracranial parasitic infections (e.g., cysticercus, encapsulated worms), etc. Acute infections such as influenza pneumonia and other diseases. 2, vascular lesions: subarachnoid space hemorrhage, cerebral hemorrhage, cerebral thrombosis, cerebral embolism, hypertensive encephalopathy, cerebral blood supply deficiency, cerebrovascular malformation, etc. 3.Occupying lesions: headache caused by increased intracranial pressure due to cranial tumor, intracranial metastatic cancer, inflammatory demyelinating pseudotumor, etc. 4.Cephalofacial and cervical neuropathy: Neuralgia of head and face: such as trigeminal nerve, linguopharyngeal nerve and occipital neuralgia. Headache caused by head and facial diseases such as eye, ear, nose and dental diseases. Cervical spondylosis and other neck diseases cause head and neck pain. 5.Systemic diseases: Headache caused by hypertension, anemia, pulmonary encephalopathy, heat stroke, etc. 6.Cranial trauma: such as concussion, brain contusion, subdural hematoma, intracranial hematoma, sequelae of traumatic brain injury. 7.Poison and drug poisoning: such as alcohol, carbon monoxide, organic phosphorus, drugs (such as belladonna, salicylic acid) and other poisoning. 8. Internal environmental disorders and mental factors: Menstrual and menopausal headaches. Neurosis somatization disorder and hysterical headache. 9.Other: such as migraine, cluster headache (histamine headache), headache type epilepsy.