Old man Cheng, nearly 80 years old, has been suffering from stubborn headache for more than 10 years, and has been relying on headache powder to relieve pain. The patient’s headache has increased significantly over the past year, but the old man has a strong character and has not mentioned it to his family. Ten days ago the old man headache severe, drugs can not relieve, serious when he hit the wall with his head, accidentally fell, was found sent to the local hospital for examination, diagnosed with deep intracranial tumor, pituitary tumor possible, due to the poor physical condition of the elderly, thin, chronic obstructive pulmonary disease, heart disease and systemic vascular serious sclerosis and other serious medical basic diseases, surgery is extremely risky, the family referred to our hospital, Yinzhou People’s Hospital The neurosurgeons saw that the old man was tormented by long-term headache and his mental state was on the verge of collapse, the doctors were very sympathetic, and after careful analysis of his condition, they decided o perform advanced neuroendoscopic transnasal minimally invasive surgery to remove the deep intracranial pituitary tumor, and before the operation, they studied the case data together with the experienced director of the Department of Anesthesiology, Wan, and after thorough preoperative preparation, for various situations that might occur during and after the operation After 3 hours of intense surgery, the deep intracranial pituitary tumor was successfully removed with only 100ml of bleeding and the patient felt significantly better after the surgery with headache and stable vital signs. The patient is ready to be discharged from the hospital soon. In the past, it was unimaginable to do such a big operation for such an old person with serious medical basic diseases. In recent years, due to the vigorous development and introduction of international advanced minimally invasive techniques and equipment, our department has adopted minimally invasive surgical treatment for most of the patients, which is in line with the frontier of neurosurgery, so that the patients can experience less pain, shorten the hospitalization time, reduce the cost of surgical treatment and achieve good social benefits. We have achieved good social benefits.