A-hsiu is 32 years old, and she complained that in recent years she had severe headache attacks during her menstrual period, often accompanied by nausea or vomiting, and even fear of sound and light, which lasted 2-3 days each time. Sometimes she could take painkillers to reduce the headache and could still go to work, but sometimes the pain relief was not effective and she had to take time off work, which seriously affected her work and made her feel very painful.　　As a matter of fact, migraine attacks during menstruation are relatively common among women. According to our observation, headaches can occur 1-2 days before, during or 1-2 days after menstruation, only the specific one will be different. It is worth pointing out that some patients may start to have attacks only before or after menstruation or during menstruation for a period of time, however, over time, in addition to attacks before or after menstruation or during menstruation, they may also have attacks during poor sleep, bad mood, and weather changes. Because the headache attacks around or during menstruation, some people think it is a gynecological disease and go to a gynecologist. In fact, it is not a gynecological disease, but a disease of encephalopathy or neurology, and gynecologists do not see this disease. It is currently believed that fluctuations in estrogen levels during menstruation are the cause of triggering headaches, however, not all women experience headaches during menstruation, indicating that it may also be related to factors such as the psycho-spirituality of the patient and the neurological and vascular microstructure of the brain. Treatment of migraine associated with menstruation is not much different from that of general migraine.