Elevated uric acid is not the same as gout, but significantly elevated uric acid is closely related to the occurrence of gout. Elevated uric acid is a condition in which the blood uric acid level exceeds the normal reference value for uric acid in normal people. The main cause of hyperuricemia is the increase of uric acid production and the decrease of uric acid excretion. Studies have found that disorders of purine metabolism are the main cause of elevated uric acid, and the extent to which a low purine diet alone can reduce blood uric acid levels is very limited, and most patients require medication. However, not all cases of “hyperuricemia” require medication. Usually, medication is considered only when blood uric acid monitoring exceeds 540 mmol/L (9 mg/dl) or when hyperuricemia is complicated by hypertension, coronary heart disease, renal failure, obesity, etc., mainly because above this level “The crystals are deposited in joints, subcutaneous tissues and kidneys, causing arthritis, deposition under the skin, formation of gout stones in soft tissues, deposition in kidneys to form kidney stones or gouty nephropathy, deposition in blood vessels to induce arteriosclerosis and a series of clinical manifestations. Gout refers to the deposition of uric acid crystals in joints, soft tissues and cartilage, which induces acute arthritis. The metabolic basis of gout attack is due to the sudden increase or decrease of blood uric acid level, resulting in the overflow of blood uric acid from the “uric acid pool” in the body and the formation of sodium uric acid microcrystals, which causes the disease. As the standard of living improves, gout is becoming more and more common. The first attack of gout mostly affects a single joint, among which the first metatarsophalangeal joint and [toe joint of the foot are the most common, manifesting as swelling and pain in the area, dark red skin, elevated skin temperature, and severe pain that affects walking, mostly triggered by eating seafood, animal offal, beef and mutton, drinking alcohol and other high purine diet, trauma, exertion, cold, infection, surgery, etc. can also trigger a gout attack, often at night or early in the morning, sudden onset. The attack often starts suddenly at night or early in the morning and may resolve on its own after a few days to weeks. After that, it can enter a long asymptomatic period, which can last for several months or even more than 10 years before relapsing, but most people relapse within 1 year, after which the gout attacks become more frequent and the number of joints involved gradually increases, including the knee and hip joints, and more joints are involved and the kidney and cardiovascular system are also involved. Therefore, the treatment of gout should also take into account the treatment of other associated diseases, so as to more effectively reduce the blood uric acid level and reduce the frequency of gout attacks. If you have had a typical gout attack, even if you do not have any clinical symptoms afterwards, you should not treat it as a simple “hyperuricemia”. The target value for uric acid reduction is 300mmol/L (5mg/dl). The main purpose of such a uric acid reduction plan is to prevent the formation of new gout stones and to gradually dissolve the gout stones that have already formed. When it comes to the medication of gout, some patients are afraid of the medication because they worry that the uric acid-lowering medication itself hurts the liver and kidney, and they think that as long as they adhere to a low purine diet and regular exercise, or just drink a lot of soda and excessive sodium bicarbonate tablets, they can treat gout. Although there is an increase, but the body fluid is too alkaline will be easy to form stones in the body, but to the detriment of the body. If the uric acid continues to fail to meet the standard, new uric acid crystals will be precipitated, which will gradually form arteriosclerosis, gout stones, gouty nephropathy and other systemic damage. As long as there is no serious abnormality of liver and kidney function, it is completely safe to use the common drugs allopurinol and benzbromarone. However, if there are serious abnormalities in liver and kidney function, there are some new drugs available, such as febuxostat, uricase, etc.