With the development of China’s economy and the arrival of the elderly society, the incidence of chronic kidney disease is gradually increasing. According to statistics, chronic kidney disease in China has exceeded 11%, and the number of patients nationwide is over 100 million. Chronic kidney disease has become a common disease that endangers people’s lives and property security at present, and early detection and timely treatment have considerable value for patients’ prognosis. The urinary system consists of kidney, ureter, bladder and urethra, because the latter three have rich sensory nerve endings, when inflammation, stones and tumors appear, they are easily detected, so some people compare the ureter, bladder and urethra to the throat and tongue, while there are no sensory nerves inside the kidney, and kidney lesions are not easily detected before they involve other organs or cause systemic reactions, so some people compare the kidney to a mute. Many patients with kidney disease have reached a more serious stage when first diagnosed. So, how can kidney disease be detected early? First of all, we have to understand the common early manifestations of kidney disease, such as cloudy urine, blood in the naked eye, thick tea-like urine, increased urine foam, increased nocturia, swelling, back pain, general weakness, etc. Chronic kidney disease not only has urinary symptoms, but also can show manifestations of other systems, such as hypertension, pruritus, anemia and bleeding gums when kidney function is reduced, and abdominal pain and joint pain in IgA nephropathy. In spite of this, many chronic kidney diseases do not have any clinical manifestations such as occult glomerulonephritis and polycystic kidney, so you should also go to the hospital regularly for relevant examinations, such as urine routine, osmolality and ultrasound. Secondly, we should pay attention to the causes of chronic kidney disease, the most common cause of chronic kidney disease is infection, such as respiratory tract infection, tonsillitis, enteritis, etc. After these diseases are healed, we should pay attention to the manifestation of kidney disease, and we should also do relevant examinations; diabetes, hypertension and benign nephrosclerosis are gradually evolving into the main causes of chronic kidney failure, so healthy people should usually pay attention to physical exercise, diet in moderation, diabetes, hypertension Patients with diabetes, hypertension and chronic cardiovascular disease should be regularly tested for microproteinuria and urine osmolality; many kidney diseases have a tendency to gather in families, so members with a history of kidney disease in their families and a history of hereditary kidney disease should pay special attention to the relevant tests for kidney disease. Again is to control the application of nephrotoxic drugs, indiscriminate use of antibiotics, antipyretic and analgesic drugs is a common cause of chronic kidney disease. I often see some people family-owned small medicine box, a cold, a variety of discomfort, self-treatment, causing chronic kidney failure. This is a very dangerous thing, so, usually should pay special attention, aminoglycoside antibiotics (such as gentamicin, kanamycin, tobramycin, amikacin), sulfonamides (such as cotrimoxazole), antipyretic analgesics (such as ibuprofen, paracetamol), water-relieving drugs (such as mannitol), etc. are very easy to cause kidney damage, should control their dose and course; some drugs seem to be Chinese medicine, in fact, the composition of many kidney Even so, many Chinese medicines are nephrotoxic. Drugs containing aristolochic acid, such as aristolochia, tian xian teng, qing muxiang, guan mu teng, searched bone wind, vermilion lotus, and hosin can cause serious kidney damage, and Chinese medicines containing the corresponding ingredients should be avoided.