Stomach cramps with watery diarrhea are mostly caused by acute gastroenteritis due to unclean diet, and should be treated with plenty of light saline, oral antidiarrheal and gastrointestinal medications. This condition usually occurs after overeating or eating contaminated food or drugs that are irritating to the stomach, such as eating undercooked string beans or bacterially contaminated meat products or leftovers, as well as eating raw and cold food or salicylates. Patients with acute gastroenteritis should first remove the cause of the disease, in particular, they should stop eating drugs or foods that are significantly stimulating to the stomach and intestines, rest in bed, and try to replenish easily digestible, light, liquid food. The patient should be given sugar and saline solution and encouraged to drink plenty of water. Gastrointestinal colic with diarrhea can be bought in pharmacies as common drugs such as gastrointestinal mucosal protectors.